Rhodium(iii)-catalyzed switchable C–H acylmethylation and annulation of 2,2′-bipyridine derivatives with sulfoxonium ylides

Abstract

A novel protocol for Rh(III)-catalyzed switchable C–H acylmethylation and annulation of 2,2′-bipyridine derivatives with sulfoxonium ylides is reported. This protocol provides a facile approach to synthesize structurally diverse acylmethylated 2,2′-bipyridine derivatives and acyl pyrido[2,3-a]indolizines with a broad range of functional group tolerance.