Radiotheranostics has attracted attention as a powerful strategy for treating cancer patients with precision medicine. We designed and synthesized a novel DOTA-based trifunctional agent, ADIBO-DOTADG-ALB (ADA), which allowed compounds with targeting ligands, radiometals, and an albumin binder to be readily prepared. ADA exhibited promising properties as a theranostic platform.
K. Nakashima, S. Iikuni, H. Watanabe and M. Ono, Chem. Commun., 2021, 57, 6432 DOI: 10.1039/D1CC00823D
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