Issue 50, 2020

A review on biological activities of Schiff base, hydrazone, and oxime derivatives of curcumin

Abstract

Curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) is the main pigment present in the turmeric rhizome and shows various biological properties. The synthesis of different derivatives is an effective way to improve the medicinal and biological properties of curcumin. Many researchers have chosen the carbonyl group of curcumin for modification and preparation of new analogues. This review critically surveys a general overview of the literature and summarizes the synthesis and biological activities of Schiff base, hydrazone and oxime derivatives of curcumin over the last decade. These compounds and also their metal complexes possess higher potency in biological activity.

Graphical abstract: A review on biological activities of Schiff base, hydrazone, and oxime derivatives of curcumin

Article information

Article type
Review Article
Submitted
30 Jun 2020
Accepted
11 Aug 2020
First published
17 Aug 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 30186-30202

A review on biological activities of Schiff base, hydrazone, and oxime derivatives of curcumin

S. Omidi and A. Kakanejadifard, RSC Adv., 2020, 10, 30186 DOI: 10.1039/D0RA05720G

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