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Issue 10, 2020
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RhIII-Catalyzed one-pot cascade synthesis of quinazolines with N-alkoxyamide as an amidating reagent

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Abstract

Novel and efficient rhodium(III)-catalyzed C–H bond activation and tandem annulation for the synthesis of structurally complex quinazolines have been successfully developed. N-alkoxyamide as an amidating reagent was first used to construct this heterocyclic skeleton in one-pot cascade reaction.

Graphical abstract: RhIII-Catalyzed one-pot cascade synthesis of quinazolines with N-alkoxyamide as an amidating reagent

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Article information


Submitted
17 Jan 2020
Accepted
28 Mar 2020
First published
31 Mar 2020

Org. Chem. Front., 2020,7, 1230-1234
Article type
Research Article

RhIII-Catalyzed one-pot cascade synthesis of quinazolines with N-alkoxyamide as an amidating reagent

H. Xu, Y. Zhu, J. Yang, X. Chai and L. Dong, Org. Chem. Front., 2020, 7, 1230
DOI: 10.1039/D0QO00084A

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