Jump to main content
Jump to site search


Straightforward Access to Densely Substituted Chiral Succinimides through Enantioselective Organocatalyzed Michael Addition of α-Alkyl-Cyclic Ketones to Maleimides

Abstract

A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary-tertiary carbon stereocenter sequence in good yields, high diastereo- and enantioselectivities through enantioselective conjugate addition of unreactive α-alkyl cyclic ketones to maleimides under microwave-assisted conditions.

Back to tab navigation

Supplementary files

Article information


Submitted
11 Dec 2019
Accepted
06 Feb 2020
First published
13 Feb 2020

Org. Chem. Front., 2020, Accepted Manuscript
Article type
Research Article

Straightforward Access to Densely Substituted Chiral Succinimides through Enantioselective Organocatalyzed Michael Addition of α-Alkyl-Cyclic Ketones to Maleimides

L. WEI, L. CHEN, F. Le Bideau, P. Retailleau and F. Dumas, Org. Chem. Front., 2020, Accepted Manuscript , DOI: 10.1039/C9QO01463B

Social activity

Search articles by author

Spotlight

Advertisements