Issue 43, 2020
From the journal:

Dalton Transactions

Sn(iv) N-confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region†

Balaji Babu, ORCID logo a   John Mack ORCID logo *a  and  Tebello Nyokong ORCID logo *a  

* Corresponding authors

a Institute for Nanotechnology Innovation. Department of Chemistry, Rhodes University, Makhanda, South Africa

Abstract

The utility of Sn(IV) N-confused porphyrin (SnNCP) for use as photosensitizer dyes in photodynamic therapy is investigated. SnNCP has an unusually high singlet oxygen quantum yield of 0.72 in DMSO. IC50 values of 1.6 and 12.8 μM were obtained against MCF-7 cells upon irradiation with 660 and 780 nm LEDs.

Graphical abstract: Sn(iv) N-confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region

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Article information

DOI
https://doi.org/10.1039/D0DT03296D
Article type
Communication
Submitted
22 Sep 2020
Accepted
22 Oct 2020
First published
22 Oct 2020

Dalton Trans., 2020,49, 15180-15183

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Sn(IV) N-confused porphyrins as photosensitizer dyes for photodynamic therapy in the near IR region

B. Babu, J. Mack and T. Nyokong, Dalton Trans., 2020, 49, 15180 DOI: 10.1039/D0DT03296D

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