Issue 19, 2020
From the journal:

Chemical Communications

Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy†

Yaqi Gu, ORCID logo a   Qi Li,a   Yichao Huang, ORCID logo a   Yingting Zhu, ORCID logo a   Yongge Wei ORCID logo *a  and  Laurent Ruhlmann ORCID logo *b  

* Corresponding authors

a Key Lab of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China
E-mail: yonggewei@mail.tsinghua.edu.cn

b Laboratoire d’Electrochimie et de Chimie Physique du Corps Solide, Institut de Chimie-UMR 7177, CNRS, Université de Strasbourg, Strasbourg Cedex 67081, France
E-mail: lruhlmann@unistra.fr

Abstract

Two novel polyoxovanadate-iodoBodipy supramolecular assemblies, named as (2I-BDP-C6)2V6 and (2I-BDP-C6)3V10, were first synthesized by the self-assembly of anionic hexavanadate and decavanadate with cationic iodoBodipy for photochemotherapy, respectively. The mechanisms for synergistic photochemotherapy of the anion–cation pairs were determined. In particular, (2I-BDP-C6)3V10 can effectively kill lung cancer cells (HepG2) by synergetic chemotherapy as well as photodynamic therapy.

Graphical abstract: Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy

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Article information

DOI
https://doi.org/10.1039/C9CC09944A
Article type
Communication
Submitted
23 Dec 2019
Accepted
31 Jan 2020
First published
05 Feb 2020

Chem. Commun., 2020,56, 2869-2872

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Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy

Y. Gu, Q. Li, Y. Huang, Y. Zhu, Y. Wei and L. Ruhlmann, Chem. Commun., 2020, 56, 2869 DOI: 10.1039/C9CC09944A

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