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Issue 15, 2019
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Reductive coupling of alkenes with unsaturated imines via a radical pathway

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Abstract

The radical reaction of unsaturated imines is challenging and remains under investigation. In this paper, reductive coupling of unsaturated imines with alkenes via a radical pathway is reported. Various unsaturated imines and alkenes could well engage in this process to deliver structurally diversified benzofurans, benzothiophenes, and medium-sized benzofuran-fused heterocycles. The protocol features mild reaction conditions and broad substrate scope.

Graphical abstract: Reductive coupling of alkenes with unsaturated imines via a radical pathway

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Publication details

The article was received on 16 May 2019, accepted on 06 Jun 2019 and first published on 10 Jun 2019


Article type: Research Article
DOI: 10.1039/C9QO00653B
Org. Chem. Front., 2019,6, 2760-2764

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    Reductive coupling of alkenes with unsaturated imines via a radical pathway

    J. Qi, H. Tang, C. Chen, S. Cui and G. Xu, Org. Chem. Front., 2019, 6, 2760
    DOI: 10.1039/C9QO00653B

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