A self-assembly of an active tumor-targeted photothermal agent for enhanced anti-inflammatory cancer therapy

Abstract

A self-assembly of an active tumor-cell-targeted photothermal agent, functionalized with a cyclic Arg-Gly-Asp peptide and ibuprofen, for killing cancer cells and eliciting anti-inflammatory responses was developed. In vitro and in vivo experiments also demonstrated that the photothermal material exhibited low cytotoxicity, good biological compatibility and excellent tumor inhibitory effects.