Issue 79, 2018

Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

Abstract

An enzyme-immobilized metal–organic framework (MOF) nanosheet system was developed as a tandem catalyst, which converted glucose into gluconic acid and H2O2, and sequentially the latter could be used to catalyze the oxidation of L-arginine to generate nitric oxide in the presence of porphyrinic MOFs as artificial enzymes under physiological pH, showing great potential in cancer depleting glucose for starving-like/gas therapy.

Graphical abstract: Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

Supplementary files

Article information

Article type
Communication
Submitted
25 Jun 2018
Accepted
10 Sep 2018
First published
12 Sep 2018

Chem. Commun., 2018,54, 11176-11179

Enzyme-immobilized metal–organic framework nanosheets as tandem catalysts for the generation of nitric oxide

P. Ling, C. Qian, F. Gao and J. Lei, Chem. Commun., 2018, 54, 11176 DOI: 10.1039/C8CC05068F

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