Issue 12, 2017

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Abstract

Green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.

Graphical abstract: Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2016
Accepted
03 Jan 2017
First published
12 Jan 2017

Chem. Commun., 2017,53, 1941-1944

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Y. Huang, M. Sumida, M. Kumazoe, K. Sugihara, Y. Suemasu, S. Yamada, S. Yamashita, J. Miyakawa, T. Takahashi, H. Tanaka, Y. Fujimura and H. Tachibana, Chem. Commun., 2017, 53, 1941 DOI: 10.1039/C6CC09504F

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