Issue 3, 2017
From the journal:

Chemical Communications

αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy†

Yan Zhou,a   Chi-Fai Chan,b   Daniel W. J. Kwong,*a   Ga-Lai Law,*b   Steven Cobb,c   Wai-Kwok Wong*a  and  Ka-Leung Wong ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, China
E-mail: wkwong@hkbu.edu.hk, klwong@hkbu.edu.hk

b Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hum, Hong Kong SAR, China

c Department of Chemistry, Durham University, Durham, UK

Abstract

We have synthesized a bifunctional erbium–porphyrin tumor imaging and PDT agent (Er–R3) that is capable of killing bladder cancer cells via its selective binding to the integrin αvβ3 isoform overexpressed on the cell membrane.

Graphical abstract: αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6CC09246B
Article type
Communication
Submitted
20 Nov 2016
Accepted
05 Dec 2016
First published
06 Dec 2016
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2017,53, 557-560

Permissions

Request permissions

αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy

Y. Zhou, C. Chan, D. W. J. Kwong, G. Law, S. Cobb, W. Wong and K. Wong, Chem. Commun., 2017, 53, 557 DOI: 10.1039/C6CC09246B

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements