On-water magnetic NiFe2O4 nanoparticle-catalyzed Michael additions of active methylene compounds, aromatic/aliphatic amines, alcohols and thiols to conjugated alkenes

Abstract

Here, we have demonstrated the Michael addition of active methylene compounds, aromatic/aliphatic amines, thiols and alcohols to conjugated alkenes using magnetic nano-NiFe₂O₄ as reusable catalyst in water. Nano-NiFe₂O₄ efficiently catalyzed the formation of C–C and C–X (X = N, S, O etc.) bond through 1,4-addition reactions.