Jump to main content
Jump to site search

Issue 70, 2016, Issue in Progress
Previous Article Next Article

Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis

Author affiliations

Abstract

Early lipid A biosynthesis is a potential antimicrobial target as this is an essential component of lipid A producing Gram-negative bacteria. Herein, we introduce a potent and highly synergistic Gram-negative selective triple-targeting antimicrobial peptide. The peptide contains a dual lipid A biosynthesis inhibiting sequence and an antimicrobial sequence.

Graphical abstract: Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 May 2016, accepted on 29 Jun 2016 and first published on 04 Jul 2016


Article type: Communication
DOI: 10.1039/C6RA11550K
Citation: RSC Adv., 2016,6, 65418-65421
  •   Request permissions

    Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis

    T. M. Postma and R. M. J. Liskamp, RSC Adv., 2016, 6, 65418
    DOI: 10.1039/C6RA11550K

Search articles by author

Spotlight

Advertisements