Preparation and preliminary application of 5-HMF@SiO2 micro-particles

Abstract

A new approach for the surficial-modification of silica with 5-HMF as a functional molecule was first designed. The infrared spectrum, X-ray photoelectron spectroscopy and elemental analysis showed that the modified-SiO₂ particles were successfully established. Full dispersion of SiO₂ and the introduction of gallic acid were confirmed to be favorable for the 5-HMF content. The retention behavior of bovine serum albumin on the modified-SiO₂ particle suggested that the novel particles could serve as a promising stationary phase on the identification of the particular proteins.