Issue 22, 2016

Three-component oxysulfenylation reaction: two simple and convenient approaches to β-alkoxy sulfides

Abstract

An unprecedented method for the synthesis of β-alkoxy sulfides via a NaI/HBr-mediated three-component oxysulfenylation reaction of alkenes with arylsulfinic acids and alcohols is reported. Furthermore, I2-promoted oxysulfenylation of alkenes using sodium arylsulfinates instead of arylsulfinic acids to synthesise various β-alkoxy sulfides is also described.

Graphical abstract: Three-component oxysulfenylation reaction: two simple and convenient approaches to β-alkoxy sulfides

Supplementary files

Article information

Article type
Paper
Submitted
25 Mar 2016
Accepted
05 May 2016
First published
10 May 2016

Org. Biomol. Chem., 2016,14, 5136-5140

Three-component oxysulfenylation reaction: two simple and convenient approaches to β-alkoxy sulfides

D. Wang, R. Zhang, W. Ning, Z. Yan and S. Lin, Org. Biomol. Chem., 2016, 14, 5136 DOI: 10.1039/C6OB00646A

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