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Issue 5, 2016
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Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes

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Abstract

Novel G-quadruplex structures are constructed by acyclic (L)-threninol nucleic acid and their synthesis and biophysical properties are described. Pyrene excimer fluorescence and circular dichroism (CD) data revealed that four strands of aTNA are oriented in antiparallel direction.

Graphical abstract: Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes

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Publication details

The article was received on 09 Dec 2015, accepted on 24 Dec 2015 and first published on 05 Jan 2016


Article type: Communication
DOI: 10.1039/C5OB02525G
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Org. Biomol. Chem., 2016,14, 1540-1544

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    Synthesis and biophysical properties of (L)-aTNA based G-quadruplexes

    V. Kumar and K. V. Gothelf, Org. Biomol. Chem., 2016, 14, 1540
    DOI: 10.1039/C5OB02525G

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