Issue 5, 2016

Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes

Abstract

Novel G-quadruplex structures are constructed by acyclic (L)-threninol nucleic acid and their synthesis and biophysical properties are described. Pyrene excimer fluorescence and circular dichroism (CD) data revealed that four strands of aTNA are oriented in antiparallel direction.

Graphical abstract: Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes

Supplementary files

Article information

Article type
Communication
Submitted
09 Dec 2015
Accepted
24 Dec 2015
First published
05 Jan 2016

Org. Biomol. Chem., 2016,14, 1540-1544

Author version available

Synthesis and biophysical properties of (L)-aTNA based G-quadruplexes

V. Kumar and K. V. Gothelf, Org. Biomol. Chem., 2016, 14, 1540 DOI: 10.1039/C5OB02525G

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