Issue 5, 2016
From the journal:

Organic & Biomolecular Chemistry

Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes†

Vipin Kumara  and  Kurt V. Gothelf*a  

* Corresponding authors

a Danish National Research Foundation Center for DNA Nanotechnology, iNANO and Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark
E-mail: kvg@chem.au.dk
Fax: +86196199

Abstract

Novel G-quadruplex structures are constructed by acyclic (L)-threninol nucleic acid and their synthesis and biophysical properties are described. Pyrene excimer fluorescence and circular dichroism (CD) data revealed that four strands of aTNA are oriented in antiparallel direction.

Graphical abstract: Synthesis and biophysical properties of (l)-aTNA based G-quadruplexes

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Article information

DOI
https://doi.org/10.1039/C5OB02525G
Article type
Communication
Submitted
09 Dec 2015
Accepted
24 Dec 2015
First published
05 Jan 2016

Org. Biomol. Chem., 2016,14, 1540-1544

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Synthesis and biophysical properties of (L)-aTNA based G-quadruplexes

V. Kumar and K. V. Gothelf, Org. Biomol. Chem., 2016, 14, 1540 DOI: 10.1039/C5OB02525G

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