Issue 21, 2016

Surface-enhanced hyper-Raman and Raman hyperspectral mapping


We investigate distributions of crystal violet and malachite green on plasmonic surfaces by principal component analysis (PCA) imaging of surface-enhanced hyper-Raman scattering (SEHRS) data. As a two-photon excited Raman scattering process, SEHRS provides chemical structure information based on molecular vibrations, but follows different selection rules than the normal, one-photon excited surface-enhanced Raman scattering (SERS). Therefore, simultaneous hyperspectral mapping using SEHRS excited at 1064 nm and SERS excited at 532 nm improves spatially resolved multivariate discrimination based on complementary vibrational information. The possibility to map distributions of the structurally similar dyes crystal violet and malachite green demonstrates the potential of this approach for multiplex imaging of complex systems.

Graphical abstract: Surface-enhanced hyper-Raman and Raman hyperspectral mapping

Supplementary files

Article information

Article type
09 Mar 2016
04 May 2016
First published
04 May 2016
This article is Open Access
Creative Commons BY license

Phys. Chem. Chem. Phys., 2016,18, 14228-14233

Author version available

Surface-enhanced hyper-Raman and Raman hyperspectral mapping

M. Gühlke, Z. Heiner and J. Kneipp, Phys. Chem. Chem. Phys., 2016, 18, 14228 DOI: 10.1039/C6CP01625A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity