Jump to main content
Jump to site search

Issue 73, 2016
Previous Article Next Article

Membrane-disrupting iridium(iii) oligocationic organometallopeptides

Author affiliations

Abstract

A series of oligoarginine peptide derivatives containing cyclometallated iridium(III) units display remarkable cytotoxicity, comparable to that of cisplatin. In vitro studies with unilamellar vesicles support a membrane-disrupting mechanism of action.

Graphical abstract: Membrane-disrupting iridium(iii) oligocationic organometallopeptides

Back to tab navigation

Supplementary files

Article information


Submitted
04 Jul 2016
Accepted
12 Aug 2016
First published
19 Aug 2016

Chem. Commun., 2016,52, 11008-11011
Article type
Communication

Membrane-disrupting iridium(III) oligocationic organometallopeptides

I. Salvadó, I. Gamba, J. Montenegro, J. Martínez-Costas, J. M. Brea, M. I. Loza, M. Vázquez López and M. E. Vázquez, Chem. Commun., 2016, 52, 11008
DOI: 10.1039/C6CC05537K

Social activity

Search articles by author

Spotlight

Advertisements