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Issue 32, 2015
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Retracted Article: Synthesis of diacylglycerol analogs bearing photoaffinity tags for labelling mammalian diacylglycerol kinase

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Abstract

Signaling lipids such as diacylglycerol (DAG), phosphatidic acid, and the phosphatidylinositol polyphosphates are site-specific ligands for protein binding partners. Herein, we report the apotheoses of our initial approach to the development of diverse probes which are vital for understanding lipid–protein interactions. When incorporated into liposomes, these probes reduce mammalian diacylglycerol kinase's (DGK) enzymatic activity in a concentration, time, and light dependent manner.

Graphical abstract: Retracted Article: Synthesis of diacylglycerol analogs bearing photoaffinity tags for labelling mammalian diacylglycerol kinase

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Publication details

The article was received on 19 Dec 2014, accepted on 02 Mar 2015 and first published on 02 Mar 2015


Article type: Communication
DOI: 10.1039/C4RA16730A
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Citation: RSC Adv., 2015,5, 25457-25461

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