Issue 80, 2015
From the journal:

RSC Advances

Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide†

Varun Penmatsa,*ab   Ruslinda A. Rahim,c   Hiroshi Kawaradad  and  Chunlei Wanga  

* Corresponding authors

a Department of Mechanical and Materials Engineering, Florida International University, Miami, USA
E-mail: vpenm001@fiu.edu

b Department of Ophthalmology and Visual Science, The Ohio State University, Columbus, USA

c Institute of Nano Electronic Engineering (INEE), Universiti Malaysia Perlis, Jln seriab-Alor setar, 01000 Kangar, Perlis, Malaysia

d School of Science and Engineering, Waseda University, Ohkubo 3-4-1, Shinjuku 169-8555, Tokyo, Japan

Abstract

The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.

Graphical abstract: Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

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Article information

DOI
https://doi.org/10.1039/C5RA10214F
Article type
Communication
Submitted
29 May 2015
Accepted
24 Jul 2015
First published
24 Jul 2015

RSC Adv., 2015,5, 65042-65047

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Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

V. Penmatsa, R. A. Rahim, H. Kawarada and C. Wang, RSC Adv., 2015, 5, 65042 DOI: 10.1039/C5RA10214F

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