Issue 21, 2015
From the journal:

Organic & Biomolecular Chemistry

A lactone-fused cyclohexadiene as a versatile platform for diversified synthesis of 5,6,5-tricyclic scaffolds†

M. Shibuya,*a   T. Sudoh,a   T. Kawamuraa  and  Y. Yamamoto*a  

* Corresponding authors

a Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan
E-mail: yamamoto-yoshi@ps.nagoya-u.ac.jp, m-shibu@ps.nagoya-u.ac.jp

Abstract

A lactone-fused cyclohexadiene, which can be readily prepared by ruthenium(III)-catalyzed [2 + 2 + 2] cyclization of an enediyne, functioned as a versatile platform for the stereoselective synthesis of differently functionalized 5,6,5-tricyclic scaffolds.

Graphical abstract: A lactone-fused cyclohexadiene as a versatile platform for diversified synthesis of 5,6,5-tricyclic scaffolds

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Article information

DOI
https://doi.org/10.1039/C5OB00729A
Article type
Communication
Submitted
13 Apr 2015
Accepted
20 Apr 2015
First published
20 Apr 2015

Org. Biomol. Chem., 2015,13, 5862-5866

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A lactone-fused cyclohexadiene as a versatile platform for diversified synthesis of 5,6,5-tricyclic scaffolds

M. Shibuya, T. Sudoh, T. Kawamura and Y. Yamamoto, Org. Biomol. Chem., 2015, 13, 5862 DOI: 10.1039/C5OB00729A

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