Jump to main content
Jump to site search

Issue 11, 2015
Previous Article Next Article

Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

Author affiliations

Abstract

Three-component reaction between RCF2CH2NH2·HCl, NaNO2 and electron-deficient alkynes significantly depends on substituent “R”. The reaction gives the fluorinated pyrazoles in high yields when “R” is a fluorine atom or a fluoroalkyl group. With other “R” unexpected products are formed.

Graphical abstract: Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Dec 2014, accepted on 27 Jan 2015 and first published on 27 Jan 2015


Article type: Paper
DOI: 10.1039/C4OB02670E
Author version
available:
Download author version (PDF)
Citation: Org. Biomol. Chem., 2015,13, 3438-3445

  •   Request permissions

    Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

    P. K. Mykhailiuk, Org. Biomol. Chem., 2015, 13, 3438
    DOI: 10.1039/C4OB02670E

Search articles by author

Spotlight

Advertisements