Jump to main content
Jump to site search

Issue 15, 2015
Previous Article Next Article

Amino-functionalized green fluorescent carbon dots as surface energy transfer biosensors for hyaluronidase

Author affiliations

Abstract

Amino-functionalized fluorescent carbon dots have been prepared by hydrothermal treatment of glucosamine with excess pyrophosphate. The produced carbon dots showed stabilized green emission fluorescence at various excitation wavelengths and pH environments. Herein, we demonstrate the surface energy transfer between the amino-functionalized carbon dots and negatively charged hyaluronate stabilized gold nanoparticles. Hyaluronidase can degrade hyaluronate and break down the hyaluronate stabilized gold nanoparticles to inhibit the surface energy transfer. The developed fluorescent carbon dot/gold nanoparticle system can be utilized as a biosensor for sensitive and selective detection of hyaluronidase by two modes which include fluorescence measurements and colorimetric analysis.

Graphical abstract: Amino-functionalized green fluorescent carbon dots as surface energy transfer biosensors for hyaluronidase

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Jan 2015, accepted on 18 Mar 2015 and first published on 18 Mar 2015


Article type: Paper
DOI: 10.1039/C5NR00070J
Citation: Nanoscale, 2015,7, 6836-6842
  •   Request permissions

    Amino-functionalized green fluorescent carbon dots as surface energy transfer biosensors for hyaluronidase

    S. Liu, N. Zhao, Z. Cheng and H. Liu, Nanoscale, 2015, 7, 6836
    DOI: 10.1039/C5NR00070J

Search articles by author

Spotlight

Advertisements