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Issue 9, 2015
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In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

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Abstract

An in situ template fabrication of inorganic nanoparticles using carboxylated PEG-dendritic block copolymers of the GATG family is described as a function of the dendritic block generation, the metal (Au, CdSe) and metal molar ratio. The biocompatibility of the generated nanoparticles analysed in terms of their aggregation in physiological media, cytotoxicity and uptake by macrophages relates to the PEG density of the surface of the hybrids.

Graphical abstract: In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

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The article was received on 18 Oct 2014, accepted on 07 Dec 2014 and first published on 08 Dec 2014


Article type: Paper
DOI: 10.1039/C4NR06155A
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Citation: Nanoscale, 2015,7, 3933-3940
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    In situ nanofabrication of hybrid PEG-dendritic–inorganic nanoparticles and preliminary evaluation of their biocompatibility

    A. Sousa-Herves, C. Sánchez Espinel, A. Fahmi, Á. González-Fernández and E. Fernandez-Megia, Nanoscale, 2015, 7, 3933
    DOI: 10.1039/C4NR06155A

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