Issue 31, 2015

Water proton NMR—a sensitive probe for solute association

Abstract

It is found that the transverse relaxation rate R2 of the water protons can be used to quantify protein aggregation and surfactant micellization in water. The simplicity and high intensity of the water proton signal enables non-invasive chemical analysis not readily achievable through solute proton signals, such as inspecting finished biologic products.

Graphical abstract: Water proton NMR—a sensitive probe for solute association

Supplementary files

Article information

Article type
Communication
Submitted
26 Jan 2015
Accepted
11 Mar 2015
First published
12 Mar 2015

Chem. Commun., 2015,51, 6804-6807

Author version available

Water proton NMR—a sensitive probe for solute association

Y. Feng, M. B. Taraban and Y. B. Yu, Chem. Commun., 2015, 51, 6804 DOI: 10.1039/C5CC00741K

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