Issue 31, 2015

Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy

Abstract

In this work, we discovered that polypyrrole nanoparticles (PPy NPs) displayed a low non-specific protein adsorption. We herein present the first PPy NP-based biosensing platform for intracellular mRNA detection in living cells. We also demonstrate that PPy NPs exhibit high NIR absorbance and can be utilized for cancer photothermal therapy.

Graphical abstract: Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy

Supplementary files

Article information

Article type
Communication
Submitted
06 Feb 2015
Accepted
11 Mar 2015
First published
11 Mar 2015

Chem. Commun., 2015,51, 6800-6803

Author version available

Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy

K. Ke, L. Lin, H. Liang, X. Chen, C. Han, J. Li and H. Yang, Chem. Commun., 2015, 51, 6800 DOI: 10.1039/C5CC01129A

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