Issue 72, 2015

Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin

Abstract

Astrosterioside A, a sulfated steroidal hexasaccharide isolated from starfish Astropecten monacanthus showing potent anti-inflammatory activity, was synthesized in a convergent linear sequence of 24 steps and in 6.8% overall yield from adrenosterone.

Graphical abstract: Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin

Supplementary files

Article information

Article type
Communication
Submitted
09 Jun 2015
Accepted
22 Jul 2015
First published
24 Jul 2015

Chem. Commun., 2015,51, 13826-13829

Author version available

Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin

Y. Dai and B. Yu, Chem. Commun., 2015, 51, 13826 DOI: 10.1039/C5CC04734J

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