Issue 59, 2015

Organocatalytic asymmetric reaction of indol-2-yl carbinols with enamides: synthesis of chiral 2-indole-substituted 1,1-diarylalkanes

Abstract

The chiral phosphoramide-catalyzed asymmetric reaction of indol-2-yl carbinols with enamides is presented. The method provided an efficient and novel way for the synthesis of chiral 2-indole-substituted 1,1-diarylalkane derivatives.

Graphical abstract: Organocatalytic asymmetric reaction of indol-2-yl carbinols with enamides: synthesis of chiral 2-indole-substituted 1,1-diarylalkanes

Supplementary files

Article information

Article type
Communication
Submitted
22 Apr 2015
Accepted
12 Jun 2015
First published
12 Jun 2015

Chem. Commun., 2015,51, 11844-11847

Organocatalytic asymmetric reaction of indol-2-yl carbinols with enamides: synthesis of chiral 2-indole-substituted 1,1-diarylalkanes

C. Liu and F. Han, Chem. Commun., 2015, 51, 11844 DOI: 10.1039/C5CC03345D

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