Dioxygenation of cysteamine to hypotaurine at a tris(pyrazolyl)borate iron(ii) unit – cysteamine dioxygenase mimicking?

Abstract

A novel complex Tp^Me,PhFe(SCH₂CH₂NH₂) has been synthesized as a speculative model for ADO. Indeed its reaction with O₂ led to the dioxygenation of the S atom and thus to hypotaurine. This finding may allow us to draw conclusions on the constitution of the ADO active site, whose structure is still unknown.