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Issue 2, 2015
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Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles

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Abstract

Mesoporous silica coated upconverting nanoparticles are loaded with the anticancer drug doxorubicin and grafted with ruthenium complexes as photoactive molecular valves. Drug release was triggered by 974 nm light with 0.35 W cm−2. Such low light intensity minimized overheating problems and prevented photodamage to biological samples.

Graphical abstract: Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles

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Publication details

The article was received on 22 Sep 2014, accepted on 11 Nov 2014 and first published on 11 Nov 2014


Article type: Communication
DOI: 10.1039/C4CC07489K
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Citation: Chem. Commun., 2015,51, 431-434
  • Open access: Creative Commons BY license
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    Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles

    S. He, K. Krippes, S. Ritz, Z. Chen, A. Best, H. Butt, V. Mailänder and S. Wu, Chem. Commun., 2015, 51, 431
    DOI: 10.1039/C4CC07489K

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