Jump to main content
Jump to site search

Issue 9, 2014
Previous Article Next Article

The template role of caffeine in its one-step encapsulation in MOF NH2-MIL-88B(Fe)

Author affiliations

Abstract

A simple and efficient one-step encapsulation of caffeine was carried out in MOF NH2-MIL-88B(Fe) and compared to the traditional three-stage synthesis–activation–encapsulation procedure. Caffeine was added to the synthesis solution of a MOF whose structure was formed around the caffeine itself. The caffeine loading was 35 wt%. The presence of this molecule in the synthesis solution led to swollen CAF@NH2-MIL-88B(Fe) when a different framework (NH2-MIL-53(Fe)) was obtained without caffeine. For comparison, the ex situ encapsulation of caffeine was also carried out in NH2-MIL-88B(Fe), once this material was obtained upon activation of NH2-MIL-53(Fe). The release of caffeine and aminoterephthalic acid (the ligand used to obtain MOFs) from different materials was studied both in water and phosphate buffered saline (PBS). Caffeine plays the role of a structure directing agent or template since its presence led to obtaining a different MOF. In addition, caffeine contributed to the liquid phase stability of the MOF, as demonstrated through the release of the ligand from both CAF@NH2-MIL-88B(Fe) (slower release) and NH2-MIL-88B(Fe) (faster release). Chemical and structural evidence indicated hydrogen bond interactions between caffeine and MOF.

Graphical abstract: The template role of caffeine in its one-step encapsulation in MOF NH2-MIL-88B(Fe)

Back to tab navigation

Supplementary files

Article information


Submitted
02 Dec 2013
Accepted
12 Dec 2013
First published
13 Dec 2013

J. Mater. Chem. B, 2014,2, 1144-1151
Article type
Paper
Author version available

The template role of caffeine in its one-step encapsulation in MOF NH2-MIL-88B(Fe)

N. Liédana, P. Lozano, A. Galve, C. Téllez and J. Coronas, J. Mater. Chem. B, 2014, 2, 1144
DOI: 10.1039/C3TB21707H

Social activity

Search articles by author

Spotlight

Advertisements