Issue 60, 2014

Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

Abstract

In the current work, we labelled human hematopoietic stem cells with polymeric nanoparticles (NPs) that can be tracked by Magnetic Resonance Imaging (MRI) and studied their effect on cell metabolism, proliferation, secretomics, genomics and differentiation. We showed that NPs had no effect on the stem cell differentiation program but affected their paracrine activity.

Graphical abstract: Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
02 May 2014
Accepted
02 Jul 2014
First published
02 Jul 2014

RSC Adv., 2014,4, 31706-31709

Author version available

Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

S. Aday, J. Paiva, S. Sousa, R. S. M. Gomes, S. Pedreiro, P. So, C. A. Carr, L. Cochlin, A. C. Gomes, A. Paiva and L. Ferreira, RSC Adv., 2014, 4, 31706 DOI: 10.1039/C4RA04041D

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