Issue 4, 2014
From the journal:

RSC Advances

A noncovalent Ru(phen)32+@CNTs nanocomposite and its application as a solid-state electrochemiluminescence signal probe

Guofeng Gui,ab   Ying Zhuo,a   Yaqin Chai,*a   Ni Liao,a   Min Zhao,a   Jing Han,a   Yun Xianga  and  Ruo Yuan*a  

* Corresponding authors

a Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China
E-mail: yqchai@swu.edu.cn, yuanruo@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

b College of Chemistry and Chemical Engineering, Bijie University, Guizhou 551700, PR China

Abstract

A simple label-free electrochemiluminescence (ECL) aptasensor was constructed for the detection of thrombin (TB). We explored the possibility of using π–π stacking to synthesis Ru(phen)32+-encapsulated CNTs nanocomposites (Ru(phen)32+@CNTs), which were immobilized on a glassy carbon electrode (GCE) surface by nafion to form the Ru(phen)32+@CNTs-Nf film as an ECL signal probe. Hollow gold nanospheres (HGNPs) were adsorbed onto the modified electrode to immobilize thrombin binding aptamer (TBA). When TB is bound by its TBA, the TB–TBA complex is electrical inertia, resulting in the decrease of ECL intensity. This work provided a new method for immobilizing the luminophore on an electrode surface and would extend the application of CNTs.

Graphical abstract: A noncovalent Ru(phen)32+@CNTs nanocomposite and its application as a solid-state electrochemiluminescence signal probe

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Article information

DOI
https://doi.org/10.1039/C3RA45641B
Article type
Paper
Submitted
08 Oct 2013
Accepted
15 Nov 2013
First published
20 Nov 2013

RSC Adv., 2014,4, 1955-1960

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A noncovalent Ru(phen)32+@CNTs nanocomposite and its application as a solid-state electrochemiluminescence signal probe

G. Gui, Y. Zhuo, Y. Chai, N. Liao, M. Zhao, J. Han, Y. Xiang and R. Yuan, RSC Adv., 2014, 4, 1955 DOI: 10.1039/C3RA45641B

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