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Issue 19, 2014
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Enantioselective imine reduction catalyzed by imine reductases and artificial metalloenzymes

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Abstract

Adding value to organic synthesis. Novel imine reductases enable the enantioselective reduction of imines to afford optically active amines. Likewise, novel bioinspired artificial metalloenzymes can perform the same reaction as well. Emerging proof-of-concepts are herein discussed.

Graphical abstract: Enantioselective imine reduction catalyzed by imine reductases and artificial metalloenzymes

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Article information


Submitted
07 Nov 2013
Accepted
24 Feb 2014
First published
24 Feb 2014

Org. Biomol. Chem., 2014,12, 2989-2992
Article type
Review Article
Author version available

Enantioselective imine reduction catalyzed by imine reductases and artificial metalloenzymes

D. Gamenara and P. Domínguez de María, Org. Biomol. Chem., 2014, 12, 2989
DOI: 10.1039/C3OB42205D

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