Issue 97, 2014
From the journal:

Chemical Communications

A lithium-rich composite metal oxide used as a SALDI-MS matrix for the determination of small biomolecules†

Ze Li,a   Yi-Wei Zhang,a   Yue-Long Xin,a   Yu Bai,*a   Heng-Hui Zhoua  and  Hu-Wei Liu*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
E-mail: hwliu@pku.edu.cn
Fax: +86-10-62751708
Tel: +86-10-62754976

Abstract

A lithium-rich composite metal oxide was evaluated as a novel matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS). The low background interference and lithium-rich feature made it a highly efficient matrix for the analysis of small molecules with high reproducibility, sensitivity and strong salt tolerance.

Graphical abstract: A lithium-rich composite metal oxide used as a SALDI-MS matrix for the determination of small biomolecules

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Article information

DOI
https://doi.org/10.1039/C4CC07479C
Article type
Communication
Submitted
22 Sep 2014
Accepted
16 Oct 2014
First published
16 Oct 2014

Chem. Commun., 2014,50, 15397-15399

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A lithium-rich composite metal oxide used as a SALDI-MS matrix for the determination of small biomolecules

Z. Li, Y. Zhang, Y. Xin, Y. Bai, H. Zhou and H. Liu, Chem. Commun., 2014, 50, 15397 DOI: 10.1039/C4CC07479C

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