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Issue 99, 2014
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Assembly, postsynthetic modification and hepatocyte targeting by multiantennary, galactosylated soft structures

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Abstract

Enzyme modifiable, hollow self-assembled structures offer an excellent scope for multiantennary delivery vectors. Herein, we report synthesis and applications of bis-galactose lysine based supramolecular ensembles, which possess surface galactose moieties amenable to enzymatic modifications. This post-synthetic modification generates reactive aldehyde groups, which could possibly serve as dynamic anchors for crosslinking and cell adhesion.

Graphical abstract: Assembly, postsynthetic modification and hepatocyte targeting by multiantennary, galactosylated soft structures

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Article information


Submitted
08 Sep 2014
Accepted
23 Oct 2014
First published
27 Oct 2014

Chem. Commun., 2014,50, 15752-15755
Article type
Communication
Author version available

Assembly, postsynthetic modification and hepatocyte targeting by multiantennary, galactosylated soft structures

A. Thomas, A. Shukla, S. Sivakumar and S. Verma, Chem. Commun., 2014, 50, 15752
DOI: 10.1039/C4CC07074G

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