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Issue 93, 2014
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Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative

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Abstract

A tetra-ortho-chloro substituted azobenzene unit was incorporated into a photoswitchable tethered ligand for ionotropic glutamate receptors. This compound confers the modified protein with the unusual optical responses of the substituted azo scaffold permitting channel opening with yellow and red light and channel closing with blue light.

Graphical abstract: Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative

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Publication details

The article was received on 22 Aug 2014, accepted on 06 Oct 2014 and first published on 06 Oct 2014


Article type: Communication
DOI: 10.1039/C4CC06612J
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Citation: Chem. Commun., 2014,50, 14613-14615
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    Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative

    A. Rullo, A. Reiner, A. Reiter, D. Trauner, E. Y. Isacoff and G. A. Woolley, Chem. Commun., 2014, 50, 14613
    DOI: 10.1039/C4CC06612J

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