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Issue 56, 2014
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Microwave-assisted preparation of nucleoside-phosphoramidites

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Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability.

Graphical abstract: Microwave-assisted preparation of nucleoside-phosphoramidites

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The article was received on 25 Apr 2014, accepted on 16 May 2014 and first published on 16 May 2014

Article type: Communication
DOI: 10.1039/C4CC03092C
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Citation: Chem. Commun., 2014,50, 7463-7465

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    Microwave-assisted preparation of nucleoside-phosphoramidites

    G. Meher, T. Efthymiou, M. Stoop and R. Krishnamurthy, Chem. Commun., 2014, 50, 7463
    DOI: 10.1039/C4CC03092C

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