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Issue 10, 2014
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Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells

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Abstract

To create an effective well-ordered delivery platform still remains a challenge. Herein we fabricate vertically aligned alumina nanowire arrays via atomic layer deposition templated by carbon nanotubes. Using these arrays, a caspase-3/7 inhibitor was delivered into DC 2.4 cells and blocked apoptosis, as confirmed by fluorescence microscopy.

Graphical abstract: Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells

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Supplementary files

Article information


Submitted
22 Oct 2013
Accepted
07 Dec 2013
First published
09 Dec 2013

Chem. Commun., 2014,50, 1234-1237
Article type
Communication

Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells

L. Lampert, B. Timonen, S. Smith, B. Davidge, H. Li, J. F. Conley, J. D. Singer and J. Jiao, Chem. Commun., 2014, 50, 1234
DOI: 10.1039/C3CC48088G

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