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Issue 21, 2014
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Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes

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Abstract

The interaction of human-derived chondrocytes and thin hyaluronan layers was studied using the quartz crystal microbalance with dissipation (QCM-D) technique combined with light microscopy. This approach allowed unique real-time monitoring of the interface between the cells and the sensor surface. Our results suggest that the hyaluronan layer is rapidly degraded by chondrocytes.

Graphical abstract: Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes

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Publication details

The article was received on 29 Jul 2014, accepted on 25 Aug 2014 and first published on 26 Aug 2014


Article type: Communication
DOI: 10.1039/C4AN01393J
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Citation: Analyst, 2014,139, 5350-5353
  • Open access: Creative Commons BY license
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    Acoustic monitoring of changes in well-defined hyaluronan layers exposed to chondrocytes

    E. Nilebäck, L. Enochson, N. Altgärde, M. Schnabelrauch, A. Lindahl, S. Svedhem and A. Kunze, Analyst, 2014, 139, 5350
    DOI: 10.1039/C4AN01393J

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