Issue 45, 2013
From the journal:

RSC Advances

A biotin–streptavidin signal amplification strategy for a highly sensitive chemiluminescent immunoassay for chicken interferon-γ†

Zhanjun Yang,*a   Shufen Luo,a   Hua Dai,a   Juan Li,a   Xin'an Jiao*b  and  Xiaoya Hua  

* Corresponding authors

a College of Chemistry and Chemical Engineering, School of Medicine, Yangzhou University, Yangzhou 225002, P.R. China
E-mail: zjyang@yzu.edu.cn
Fax: +86 514 87975244
Tel: +86 514 87972034

b Jiangsu Key Lab of Zoonosis, Yangzhou University, Yangzhou 225002, P.R. China
E-mail: jiao@yzu.edu.cn

Abstract

The first example of a biotin–streptavidin signal amplification strategy was developed for a highly sensitive chemiluminescent immunoassay for chicken interferon-γ at sub-picogram per millilitre level. This approach displays a 415-fold increase in the detection limit in comparison with conventional methods.

Graphical abstract: A biotin–streptavidin signal amplification strategy for a highly sensitive chemiluminescent immunoassay for chicken interferon-γ

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Article information

DOI
https://doi.org/10.1039/C3RA44325F
Article type
Communication
Submitted
13 Aug 2013
Accepted
16 Sep 2013
First published
17 Sep 2013

RSC Adv., 2013,3, 22868-22871

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A biotin–streptavidin signal amplification strategy for a highly sensitive chemiluminescent immunoassay for chicken interferon-γ

Z. Yang, S. Luo, H. Dai, J. Li, X. Jiao and X. Hu, RSC Adv., 2013, 3, 22868 DOI: 10.1039/C3RA44325F

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