Issue 45, 2013
From the journal:

RSC Advances

PEG/lecithin–liquid-crystalline composite hydrogels for quasi-zero-order combined release of hydrophilic and lipophilic drugs†

Hongbin Zhang,a   Rui Hao,a   Xiangkui Ren,b   Li Yu,a   Huai Yang*a  and  Haifeng Yu*a  

* Corresponding authors

a Department of Advanced Materials and Nanotechnology, College of Engineering, Peking University, Beijing, P. R. China
E-mail: yuhaifeng@pku.edu.cn, yanghuai@coe.pku.edu.cn
Tel: +86-010-62764244

b College of Chemistry and Molecular Engineering, Peking University, Beijing, P. R. China

Abstract

Liquid crystalline microphase formed in PEG/lecithin hydrogels provides suppressed release of hydrophilic drugs but accelerated release for lipophilic drugs, achieving quasi-zero-order release of drugs with different water solubility.

Graphical abstract: PEG/lecithin–liquid-crystalline composite hydrogels for quasi-zero-order combined release of hydrophilic and lipophilic drugs

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Article information

DOI
https://doi.org/10.1039/C3RA44080J
Article type
Communication
Submitted
01 Aug 2013
Accepted
07 Oct 2013
First published
08 Oct 2013

RSC Adv., 2013,3, 22927-22930

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PEG/lecithin–liquid-crystalline composite hydrogels for quasi-zero-order combined release of hydrophilic and lipophilic drugs

H. Zhang, R. Hao, X. Ren, L. Yu, H. Yang and H. Yu, RSC Adv., 2013, 3, 22927 DOI: 10.1039/C3RA44080J

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