An efficient one-pot three-component reaction for the synthesis of novel functionalized pyrano[3,2-c]coumarins catalyzed by Na2CO3 in aqueous medium

Pallabi Borah; P. Seetham Naidu; Swarup Majumder; Pulak J. Bhuyan

doi:10.1039/C3RA43484B

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An efficient one-pot three-component reaction for the synthesis of novel functionalized pyrano[3,2-c]coumarins catalyzed by Na₂CO₃ in aqueous medium†

Pallabi Borah,^a P. Seetham Naidu,^a Swarup Majumder^a and Pulak J. Bhuyan*^a

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* Corresponding authors

^a Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat 785006, Assam, India
E-mail: pulak_jyoti@yahoo.com
Fax: +91-376-2370011
Tel: +91-376-2370121

Abstract

An efficient green method for the synthesis of novel functionalized pyrano[3,2-c]coumarins from a one-pot three-component reaction of 4-hydroxycoumarins, dialkylacetylenedicarboxylates and alkyl acetonitriles catalyzed by Na₂CO₃ in aqueous medium was developed. The pure products were obtained in high yield from a simple work-up procedure.

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DOI: https://doi.org/10.1039/C3RA43484B
Article type: Paper
Submitted: 09 Jul 2013
Accepted: 12 Aug 2013
First published: 13 Aug 2013

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RSC Adv., 2013,3, 20450-20455

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An efficient one-pot three-component reaction for the synthesis of novel functionalized pyrano[3,2-c]coumarins catalyzed by Na₂CO₃ in aqueous medium

P. Borah, P. S. Naidu, S. Majumder and P. J. Bhuyan, RSC Adv., 2013, 3, 20450 DOI: 10.1039/C3RA43484B

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