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Issue 11, 2013
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Imidazolium salts as antifungal agents: activity against emerging yeast pathogens, without human leukocyte toxicity

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Abstract

This study demonstrates the excellent in vitro antifungal activity profile of imidazolium ionic liquids (ILs) against species of opportunistic human mycoses. Several ILs were identified as more effective and less harmful than commercially available antifungal medications. Frequently, emerging yeast pathogens are resistant against commercial antifungal agents and, as a consequence, this class of imidazolium ILs represents a promising breakthrough in their treatment.

Graphical abstract: Imidazolium salts as antifungal agents: activity against emerging yeast pathogens, without human leukocyte toxicity

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Publication details

The article was received on 31 Jul 2013, accepted on 02 Sep 2013 and first published on 03 Sep 2013


Article type: Concise Article
DOI: 10.1039/C3MD00222E
Med. Chem. Commun., 2013,4, 1457-1460

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    Imidazolium salts as antifungal agents: activity against emerging yeast pathogens, without human leukocyte toxicity

    H. S. Schrekker, R. K. Donato, A. M. Fuentefria, V. Bergamo, L. F. Oliveira and M. M. Machado, Med. Chem. Commun., 2013, 4, 1457
    DOI: 10.1039/C3MD00222E

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