Jump to main content
Jump to site search

Issue 2, 2013
Previous Article Next Article

Selective copper catalysed aromatic N-arylation in water

Author affiliations

Abstract

4,7-Dipyrrolidinyl-1,10-phenanthroline (DPPhen) was identified as an efficient ligand for copper catalysed selective aromatic N-arylation in water. N-Arylation of indoles, imidazoles and purines proceeds with moderate to excellent yields and complete selectivity over aliphatic amines. Aqueous medium and the possibility for low metal and ligand loadings give the process a benign environmental profile.

Graphical abstract: Selective copper catalysed aromatic N-arylation in water

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Oct 2012, accepted on 11 Nov 2012 and first published on 12 Nov 2012


Article type: Communication
DOI: 10.1039/C2GC36589H
Citation: Green Chem., 2013,15, 336-340
  •   Request permissions

    Selective copper catalysed aromatic N-arylation in water

    J. Engel-Andreasen, B. Shimpukade and T. Ulven, Green Chem., 2013, 15, 336
    DOI: 10.1039/C2GC36589H

Search articles by author

Spotlight

Advertisements