Issue 20, 2012
From the journal:

RSC Advances

Novel syntheses of pyrrolo[2,1-a]isoquinolines via1,3-dipolar cycloaddition between Isoquinoliniums and alkynes†

Yongjia Shang,*a   Lifen Wang,a   Xinwei Hea  and  Min Zhanga  

* Corresponding authors

a Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Key Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, PR China
E-mail: shyj@mail.ahnu.edu.cn
Fax: +86-553-3883517
Tel: +86-553-3937138

Abstract

A straightforward synthesis of pyrrolo[2,1-a]isoquinolines has been achieved from 1,3-dipolar cycloaddition reaction between isoquinoliniums and alkynes in the presence of K2CO3, and features with versatility, easy operation and mild reaction conditions. 22 examples were synthesized.

Graphical abstract: Novel syntheses of pyrrolo[2,1-a]isoquinolines via 1,3-dipolar cycloaddition between Isoquinoliniums and alkynes

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Article information

DOI
https://doi.org/10.1039/C2RA21116E
Article type
Paper
Submitted
04 Feb 2012
Accepted
13 Jun 2012
First published
13 Jun 2012

RSC Adv., 2012,2, 7681-7688

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Novel syntheses of pyrrolo[2,1-a]isoquinolines via 1,3-dipolar cycloaddition between Isoquinoliniums and alkynes

Y. Shang, L. Wang, X. He and M. Zhang, RSC Adv., 2012, 2, 7681 DOI: 10.1039/C2RA21116E

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