Issue 10, 2012

Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines

Abstract

Diverse 11H-indeno[1,2-c]quinolines are produced via a palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile. This conversion tolerates a wide variety of functionality and substitution patterns on the 11H-indeno[1,2-c]quinoline ring.

Graphical abstract: Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines

Supplementary files

Article information

Article type
Paper
Submitted
20 Oct 2011
Accepted
13 Dec 2011
First published
13 Dec 2011

Org. Biomol. Chem., 2012,10, 1969-1975

Palladium-catalyzed three-component reaction of 2-alkynylbromobenzene, 2-alkynylaniline, and electrophile: an efficient pathway for the synthesis of diverse 11H-indeno[1,2-c]quinolines

X. Pan, Y. Luo and J. Wu, Org. Biomol. Chem., 2012, 10, 1969 DOI: 10.1039/C2OB06764A

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