A general chemical synthesis platform for crosslinking multivalent single chain variable fragments
Abstract
Multivalent single chain variable fragments (scFv) show increased affinity to tumor-associated
a
Chemistry Department, University of California Davis, One Shields Avenue, Davis, CA, USA
E-mail:
Gervay@chem.ucdavis.edu
Fax: +1 530-754-6915
Tel: +1 530-754-9577
b Radiodiagnosis and Therapy Section, Internal Medicine, University of California Medical Center, Sacramento, CA, USA
c Department of Chemistry, Central Michigan University, Pleasant, Mount, MI, USA
Multivalent single chain variable fragments (scFv) show increased affinity to tumor-associated
J. G. Schellinger, A. Kudupudi, A. Natarajan, W. Du, S. J. DeNardo and J. Gervay-Hague, Org. Biomol. Chem., 2012, 10, 1521 DOI: 10.1039/C0OB01259A
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