2, 2′-(phenylazanediyl) diacetic acid modified Fe3O4@PEI for selective removal of cadmium ions from blood

Abstract

A water-dispersible and supermagnetic nanocomposite (PAD-PEG-Fe₃O₄@PEI) has been successfully synthesized using polyethylenimine (PEI, Mol MW = 10000) coated supermagnetic Fe₃O₄–NH₂ which was modified with 2, 2′-(phenylazanediyl) diacetic acid (PAD) through the bridge of poly(ethylene glycol) (PEG, Mol MW = 2000). The average particle size of PAD-PEG-Fe₃O₄@PEI was determined by TEM, and was about 50 nm. From magnetic hysteresis cycles for PAD-PEG-Fe₃O₄@PEI at room temperature, the saturation magnetization (Ms) was shown to be 58.14 emu g⁻¹. Inductively coupled plasma spectrometry (ICP) analysis showed that the designed magnetic nanocomposite can remove 98% and 80% of Cd²⁺ from water and blood, respectively.